Technical Information
NEOGUARD™ - Neoguard™ Technical Information Sheet (71Kb)NeoGuard™ is the first and only USDA-approved safe and efficacious vaccine used as an aid in the reduction of abortions caused by Neospora caninum.
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NEOGUARD™ - Neoguard™ Technical Bulletin 1 (51Kb)- Seven hundred fifty-seven cows from seven farms were used in the study.
- The herds used had no previous history of reproductive problems.
- Vaccinates received two injections of Neospora caninum vaccine 21 to 28 days apart.
- Controls received two injections of saline at the same interval.
- Cattle were pregnancy tested by palpation 60 to 90 days following the second vaccination.
- The Neospora caninum vaccine is safe for use in healthy, pregnant dairy cattle.
- Injection site reactions were insignificant or similar to those seen with other vaccines.
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NEOGUARD™ - Neoguard™ Technical Bulletin 2 (62Kb)- Thirty-eight pregnant heifers 18 to 24 months of age were used in the study.
Treatments were as follows:
1. Control – non-vaccinates and
2. NeoGuard™, Neospora caninum vaccine, 5 mL given subcutaneously, two injections, 21 days apart.
- All heifers used in the study tested serum-negative for Neospora caninum antibodies at the beginning of the study.
- NeoGuard™ was given on days 56 and 77 of gestation.
- All heifers were challenged with a Neospora caninum challenge preparation on day 95 of gestation.
- NeoGuard™ vaccinated heifers had an increase (Pd0.05) in sample to positive (S/P) ratios at the time of challenge and 28 days post-challenge when compared to control heifers indicating a marked immunological response to the vaccination.
- NeoGuard™ vaccinated heifers had fewer (P<0.05) abortions than control heifers.
- NeoGuard™ is efficacious and safe when used in healthy, pregnant heifers as an aid in reducing abortions in cattle exposed to a challenge of Neospora caninum.
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