Nobivac™ Lyme
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Nobivac™ Lyme is a bacterin that contains two inactivated strains of Borrelia burgdorferi comprised of outer surface protein A (OspA) and outer surface protein C (OspC). It is adjuvanted to elicit a strong and protective immune response. This bacterin is approved for the vaccination of healthy dogs as an aid in the prevention of subclinical arthritis caused by B. burgdorferi.
Nobivac™ Lyme is administered subcutaneously as an initial vaccination followed by a booster 2 to 4 weeks later. It can be given to dogs beginning at 8 weeks of age. Annual re-vaccination with Nobivac™ Lyme is recommended. One-year duration of immunity data is on file at the USDA.
Reference:
1. LaFleur RL, Dant JC, Wasmoen TL, et al. Bacterin that induces anti-OspA and anti-OspC borreliacidal antibodies provides a high level of protection against canine Lyme disease. Clin Vaccine Immunol. 2009;16:253–259.