Species
Estrumate® Prostaglandin
Pharmaceutical Name
cloprostenol sodium
Features and Benefits
For intramuscular use to induce luteolysis in beef and dairy cattle. The luteolytic action of Estrumate can be utilized to manipulate the estrous cycle to better fit certain management practices, to terminate pregnancies resulting from mismatings, and to treat certain conditions associated with prolonged luteal function.
- Half-life for ESTRUMATE prostaglandin is 3 hours versus a few minutes for Lutalyse.1
Estrumate prostaglandin lasts much longer than Lutalyse. The responsiveness of the corpus luteum to prostaglandin injection increases progressively during the early and mid-stage of the estrous cycle.2
Reliable heat. - ESTRUMATE prostaglandin is a more potent luteolytic agent than Lutalyse.3
Detectable heat. - ESTRUMATE prostaglandin quickly reduces a progesterone levels4 and provides a rapid estrus response.5
Convenience. - When you’re synchronizing, nothing beats the convenience of ESTRUMATE prostaglandin:
- 50-Dose and 10-Dose Bottles
- 2-mL Dose for Heifers and Cows
1 EMEA, The European Agency for the Evaluation of Medicinal Products. “Cloprostenol and R-Cloprostenol.” Summary Report, April 1997. “Dinoprost.” Summary Report, June 1997.
2 Berardinelli, J.G., et al. Effect of prostaglandin dosage and stage of estrous cycle on the estrous response and corpus luteum function in beef heifers. Theriogenology, 32: 301-314, 1989.
3 Martineau, R. Dinoprost Versus Cloprostenol: Does Route of Injection Modulate Their Efficacy in Dairy Cattle? The Bovine Practitioner, pp. 19-19, February 2003.
4 Hayashi, K., et al. "Changes in Prostaglandin Secretion by the Regressing Bovine Corp Luteum.” Elsevier – Prostaglandins & Other Lipid Mediators. 70:339-349, 2003.
5 Seguin, B et al. Cloprostenol and Dinoprost Tromethamine in Experimental and Field Trials Treating Unobserved Estrus in Dairy Cows. The Bovine Practitioner, pp. 85-90, November 1985.
Dosage
For further information including dose rate and complete directions and warnings, please see the Product Label by clicking here.
Estrumate® Prostaglandin is a registered trademark of Schering-Plough Animal Health Corporation.